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Status: Ready for the Market

Corneal implant for the treatment of ectatic eye diseases and complicated myopia

While KERALUX is used when the visual acuity of keratoconus patients is still good enough to preserve visual acuity, MyoRing serves to improve or restore visual acuity. Vision deterioration in keratoconus patients occurs as a result of irregular deformation of the cornea due to pathological tissue weakness. MyoRing is able to correct irregular corneal geometry and restore visual acuity. For this purpose, MyoRing – an implant in the form of a closed ring made of medical plastic with shape memory – is inserted into the cornea during a minimally invasive, painless and reversible procedure which takes about 15 minutes to accomplish. The surgical method is called CISIS (Corneal Intra-Stromal Improvement Surgery). CISIS with implantation of MyoRing can draw on long-term experience of over 10 years and more than 10,000 successful procedures performed to date. CISIS and MyoRing have revolutionised keratoconus treatment. Vision improvement combined with the highest level of safety is truly unique. In the vast majority of cases, this internationally patented technology may help to avoid corneal transplantation or de facto blindness and permanently restores visual acuity. No other technique is able to accomplish this. For more detailed information please visit our website www.cisis.com.

Scientific literature

1. Fratzl P, Daxer A (1993) Structural transformation of collagen fibrils in corneal stroma during drying: An X-ray scattering study. Biophys J 64:1210-1214.

2. Daxer A, Fratzl P (1997) Collagen fibril orientation in the human corneal stroma and its implication in keratoconus. Invest Ophthalmol Vis Sci 38:121-129.

3. Daxer A, Misof K, Grabner B, Ettl A, Fratzl P. (1998) Collagen fibrils in the human corneal stroma: structure and ageing. Invest Ophthalmol Vis Sci 39:644-648.

4. Daxer A. (2007) Intracorneal ring: a good alternative to LASIK? Ophthalmology Times Europe 3:40-41.

5. Daxer A. (2008) Corneal intrastromal implantation surgery for the treatment of moderate and high myopia. J Cataract Refract Surg 34:194-198.

6. Daxer A (2008) Corneal Intrastromal Implantation Surgery. Cataract & Refractive Surgery Today Europe 3:63-64.

7. Daxer A (2009) CISIS: Reversible chirurgische Behandlung hoher Kurzsichtigkeiten und des Keratokonus. Spektrum Augenheilkd 23:39-41.

8. Daxer A (2010) Adjustable Intracorneal Ring in a Lamellar Pocket for Keratoconus. J Refract Surg 26:217-221.

9. A. Daxer, H. Mahmoud and RS Venkateswaran. (2010) Corneal IntraStromal Implantation Surgery (CISIS) for Keratoconus: One year Follow-Up. Journal of Cataract and Refractive Surgery 36:1296-1302.

10. H. Mahmoud, RS Venkateswaran and A. Daxer (2011) Implantation of a Complete Corneal Ring in an Intrastromal Pocket for Keratoconus. Journal of Refractive Surgery. 27:63-68.

11. JL Alio, DP Pinero and A Daxer (2011) Clinical Outcome after Complete Ring Implantation in Corneal Ectasia using the Femtosecond Technology. Ophthalmology 118:1282-1290.

12. A Daxer (2015) Biomechanics of Corneal Ring Implants. Cornea 34:1493-1498.

13. A Prangl-Grötzl, A Ettl, R Hörantner and A Daxer (2016) Individual Long-Term Visual Stability after MyoRing Treatment of Keratokonus. International Journal of Keratoconus and Ectatic Corneal Diseases 5:53-56.

14. A Daxer, A Ettl and R Hörantner (2017) Long-term results of MyoRing treatment of keratokonus. Journal of Optometry 10:123-129.

15. A Daxer (2017) MyoRing Treatment of Myopia. Journal of Optometry 10:194-198.